Since the 1950s, the late antique pilgrimage site Resafa-Sergiupolis and its surroundings, encompassing an area of approximately 9 km², are subject of archaeological research. As part of an interdisciplinary project of the German archaeological institute (DAI) and the TU Berlin (1997–2001, 2006–2011) various non-destructive prospection techniques were applied. These included geophysical prospections, the recording of surface features, the analysis of aerial photographs and the generation of high-resolution digital terrain models (DTMs) based on land surveying. Additionally, archaeological soundings were also excavated. The superposition of the results of these different survey methods into a CADsystem allowed a reassessment of areas with previously blurred or ambiguous results. Also, the application of these methods enabled the project to record previously unknown sites and settlement structures. For certain areas, the relative settlement sequence could also be determined.